Liposomal oligonucleotide compositions

Details Liposomal oligonucleotide compositions Liposomal oligonucleotide compositions

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 9/127 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2227989

A pharmaceutical composition comprising (A) an oligonucleotide 8 to 50 nucleotides in length, which is targeted to mRNA encoding human raf and is capable of inhibiting raf expression, entrapped in (B) sterically stabilised liposomes.

Composition pharmaceutique qui comprend (A) un oligonucléotide ayant de 8 à 50 nucléotides de longueur, qui a pour cible l'ARNm codant raf humain, et est capable d'inhiber l'expression de raf, piégé dans des (B) liposomes à stabilisation stérique.

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