A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 9/19 (2006.01) A61K 47/24 (2006.01) A61K 31/71 (1990.01)
Patent
CA 2099771
A method is disclosed for preparing a stable preliposomal powder which, when reconstituted with water or saline solution, forms a suspension of liposomes containing a polyene drug, such as nystatin. The method involves the steps of combining at least one phospholipid with a first organic solvent to form a first solution, adding a clarifying amount of water to the first solution, combining a polyene with a second organic solvent to form a second solution, combining the first and second solutions to produce a substantially clear combined solution, and then removing the organic solvents, leaving a powder.
Lenk Robert P.
Lopez-Berestein Gabriel
Mehta Reeta
Argus Pharmaceuticals Inc.
Finlayson & Singlehurst
The Board Of Regents Of The University Of Texas System
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