A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 9/00 (2006.01) A61K 38/24 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) C07K 7/23 (2006.01) C07K 14/595 (2006.01)
Patent
CA 2489919
The invention provides liposomal vehicles for encapsulating relatively high levels of water-soluble substances including immunogens directed against gastrin and gonadotropin releasing hormone. The liposome encapsulating large amounts of immunogens can be injected parentally to induce effective immune responses without exhibiting significant adverse tissue reactogenicity.
L'invention procure des véhicules liposomaux destinés à encapsuler des niveaux relativement élevés de substances solubles dans l'eau, y compris des immunogènes dirigés contre l'hormone libérant de la gastrine et de la gonadotropine. Le liposome encapsulant de grandes quantités d'immunogènes peut être injecté chez les parents pour induire des réponses immunitaires efficaces sans présenter de réactogénicié fâcheuse des tissus.
Barenholz Yechezkel
Even-Chen Simcha
Grimes Stephen
Michaeli Dov
Aphton Corporation
Moffat & Co.
Yissum Research Development Co. Of The Hebrew University Of Jeru
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