Liposome composition for immune induction

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 39/00 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2634038

It is an object of the present invention to provide a liposome composition which is able to allow the MHC class I and class II molecules of antigen-presenting cells to efficiently present an antigen substance. The present invention provides a liposome composition, which comprises an oligosaccharide-coated liposome and an antigen substance and is used to cause the MHC class I and class II molecules of an antigen-presenting cell to present an antigen peptide.

La présente invention concerne une préparation de liposomes susceptibles de présenter avec une efficacité satisfaisante une substance antigène sur une molécule du MHC de classe I ou II située sur une cellule présentant l'antigène. La préparation de liposomes comprend un liposome enrobé d'un oligosaccharide et une substance antigène, et peut être employée pour présenter un peptide antigène sur une molécule du MHC de classe I ou II située sur une cellule présentant l'antigène.

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