Liposome compositions for in vivo administration of boronic...

Details Liposome compositions for in vivo administration of boronic... Liposome compositions for in vivo administration of boronic...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 31/69 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2697042

Liposome formulations for administration of a boronic acid compound are described. The liposomes are comprised of a phospholipid having two acyl chains with between 20-22 carbon atoms in each chain and a boronic acid compound entrapped in the liposomes. In a preferred embodiment, the boronic acid compound is in the form of a complex with meglumine.

Cette invention a trait à des formules à base de liposomes servant à administrer un composé d'acide boronique. Les liposomes sont constitués d'un phospholipide à deux chaînes acyle contenant chacune entre 20 et 22 atomes de carbone et d'un composé d'acide boronique piégé dans les liposomes. Dans un mode de réalisation préféré, le composé d'acide boronique se trouve sous forme d'un complexe avec la méglumine.

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