Liposome conjugates and diagnostic methods therewith

Details Liposome conjugates and diagnostic methods therewith Liposome conjugates and diagnostic methods therewith

G - Physics

01

N

167/45

G01N 33/566 (2006.01) G01N 33/554 (2006.01) G01N 33/80 (2006.01)

Patent

CA 1198053

Liposome Conjugates and Diagnostic Methods Therewith Abstract A number of naturally occurring antibodies to human erythrocyte surface antigens are capable of combin- ing with their specific antigens (for example, Rhesus factor), but are not capable of producing visible hemagglutination. Also, the sensitivity of many diag- nostic methods, such as in human blood typing, depends upon cell agglutination. The present invention provides liposome- protein conjugates, especially useful for he- magglutination assays, having an enhanced agglutination capacity with respect to antibody from which the conju- gates are derived.

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