Liposome containing hydrophobic iodine compound

A - Human Necessities – 61 – K

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Details

A61K 49/04 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61K 47/28 (2006.01)

Patent

CA 2407654

A liposome containing a hydrophobic iodine compound such as a 1,3,5-triiodobenzene derivative having at least one substituent containing 18 or more carbon atoms as a membrane component, and an X-ray contrast medium containing the liposome for use in radiography of a vascular disease and the like.

L'invention concerne des liposomes contenant comme constituant membranaire un composé iodo hydrophobe, tel qu'un dérivé de 1,3,5- triiodobenzène, comportant au moins un substituant porteur de 18 atomes de carbone ou plus (par exemple, un dérivé du cholestérol). L'invention concerne également des agents de contraste radiographique pour le procédé utilisant le contraste, appliqué lors de troubles vasculaires, entre autres, ces agents contenant les liposomes susmentionnés.

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