A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/713 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61K 47/28 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) A61P 31/16 (2006.01)
Patent
CA 2668020
A method of treating an avian influenza viral infection using a poly ICLC formulation with improved therapeutic efficacy is disclosed. The poly ICLC is encapsulated within liposomes which provides a drug delivery system with slow sustained release characteristic and which has the ability to target the drug to sites of viral infection without causing systemic burden to normal tissues, thereby enhancing the immunological and biological activities of poly ICLC. This poly ICLC formulation has been found to be particularly effective in treating an avian influenza viral infection and in particular, an avian H5N1 influenza viral infection.
L'invention concerne un procédé destiné à traiter une infection par le virus de la grippe aviaire utilisant une formule de poly ICLC qui présente une efficacité thérapeutique améliorée. Le poly ICLC est encapsulé au sein de liposomes qui procurent un système de libération de médicament qui présente une caractéristique de libération lente soutenue et qui est susceptible d'envoyer de manière ciblée le médicament vers des sites d'infection virale sans imposer de charge systémique aux tissus normaux, améliorant ainsi l'activité immunologique et biologique du poly ICLC. Cette formule de poly ICLC s'est révélée particulièrement efficace dans le traitement d'une infection par le virus de la grippe aviaire et, en particulier, d'une infection par le virus H5N1 de la grippe aviaire.
As Represented By The Ministe R. Of National Defence Her Majesty The Queen In Right Of Canada
Nelligan O'brien Payne Llp
LandOfFree
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