Liposome preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 31/282 (2006.01) A61K 31/337 (2006.01) A61K 31/513 (2006.01) A61K 31/537 (2006.01) A61K 31/573 (2006.01) A61K 31/7068 (2006.01) A61K 33/36 (2006.01) A61K 45/00 (2006.01) A61K 47/18 (2006.01) A61K 47/24 (2006.01) A61K 47/26 (2006.01) A61K 47/28 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2640598

Disclosed is a cancer therapeutic preparation having an excellent targeting property. A sugar chain-modified liposome containing an aromatase inhibitor, an anti-androgenic agent, a lyase inhibitor, a GnRH agonist, a GnRH antagonist, an anti-angiogenic agent, a tyrosine kinase inhibitor, a serine- threonine kinase inhibitor, an antibody having an anti-cancer activity, ansamitocin, capecitabine, celmoleukin, docetaxel hydrate, gemcitabine hydrochloride, oxaliplatin, prednisolone, a tegafur-uracil blend, zinostatin stimalamer or arsenic trioxide or the like can be used as a cancer therapeutic preparation having an excellent targeting property or the like.

L'invention concerne une préparation thérapeutique visant à traiter un cancer et ayant une excellente propriété de vectorisation. L'invention concerne également un liposome avec une chaîne de sucre modifiée contenant un inhibiteur d'aromatase, un agent anti-androgénique, un inhibiteur de lyase, un agoniste de la GnRH, un antagoniste de la GnRH, un agent antiangiogenèse, un inhibiteur de tyrosine kinase, un inhibiteur de sérine-thréonine kinase, un anticorps ayant une action anticancéreuse, de l'ansamitocine, de la capécitabine, de la celmoleucine, un hydrate de docétaxel, un chlorhydrate de gemcitabine, de l'oxaliplatine, de la prednisolone, un mélange de tegafur et d'uracil, du zinostatine stimalamère ou du trioxyde d'arsenic, ou similaires, pouvant être utilisé en tant que préparation thérapeutique du cancer ayant une excellente propriété de vectorisation ou similaire.

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