Liposome preparation

Details Liposome preparation Liposome preparation

A - Human Necessities

61

K

A61K 33/24 (2006.01) A61K 9/127 (2006.01) A61K 31/555 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2409795

The present invention provides a liposome preparation containing oxaliplatin and derivatized with a hydrophilic polymer, as well as a pharmaceutical composition for treatment of tumor comprising the liposome preparation. The liposome preparation according to the present invention is characterized in that it is derivatized with a ligand. The ligand is preferably transferrin. In accordance with the invention, the uptake of a pharmaceutical agent in the liposome into tumor cells can be enhanced through transferrin receptors expressed on the surface of the tumor cells.

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