Liposome preparations

Details Liposome preparations Liposome preparations

A - Human Necessities

61

K

A61K 31/407 (2006.01) A61K 9/127 (2006.01) A61K 31/436 (2006.01) A61K 31/7042 (2006.01) A61K 47/24 (2006.01) A61P 9/10 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 37/00 (2006.01) C07D 498/18 (2006.01) C07H 7/06 (2006.01)

Patent

CA 2364257

Pipecolic acid derivative-containing liposome preparations which are excellent in the immediate action and thus usable in an urgent situation such as brain infarction. These preparations are characterized by containing pipecolic acid derivatives or pharmaceutically acceptable salts thereof, which comprise the components as described in the description, as the active ingredient and lecithin as the major component of lipids forming liposomes, without resort to cholesterol as a stabilizer.

La présente invention concerne des préparations liposomiques contenant des dérivés d'acide pipecolique, qui ont une action immédiate excellente et qui peuvent donc être utilisées dans des situations présentant un caractère d'urgence comme dans les cas d'infarctus cérébral. Ces préparations sont caractérisées par le fait qu'elles contiennent des dérivés d'acide pipecolique ou des sels pharmaceutiquement acceptables de ceux-ci. Elles comprennent les composants précités comme principe actif, et du lécithol qui est le composant principal des lipides constitutifs des liposomes, sans recourir au cholestérol pour servir de stabilisant.

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