Liposome reagents for immunoassays

G - Physics – 01 – N

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Details

G01N 33/543 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2251958

The present invention relates to the detection of a variety of analytes in a patient sample employing liposomes with associated ligand, where the ligand is capable of binding target analyte in that sample. In another aspect of the invention, the assays employ liposomes as a soluble support matrix where at least a portion of the support is associated with the ligand and the ligand is in a conformation permitting it to bind to target analyte in a patient sample.

L'invention concerne la détection d'une variété d'analytes dans un prélèvement effectué chez un patient, qui consiste à utiliser des liposomes avec un ligand associé, ce ligand étant capable de se fixer à l'analyte ciblé dans le prélèvement. Dans un autre aspect de l'invention, les dosages immunologiques mettent en application des liposomes en tant que matrice de support soluble, au moins une partie du support étant associée au ligand et le ligand présentant une forme qui lui permet de se fixer à l'analyte ciblé dans le prélèvement effectué chez le patient.

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