Liposomes capable of effectively binding the beta amyloid...

Details Liposomes capable of effectively binding the beta amyloid... Liposomes capable of effectively binding the beta amyloid...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2727417

Novel liposomes are described which are capable of effectively binding beta amyloid peptide and are useful for the treatment, prevention and diagnosis of Alzheimer's disease. Binding ability is provided by the presence in the formulation of particular natural lipids identified by the Applicant. These comprise a constant component, made up of cholesterol and sphingomyelin, and an additional variable component, made up of selected lipids.

La présente invention concerne de nouveaux liposomes qui sont capables de se lier efficacement au peptide bêta amyloïde et qui sont utiles pour le traitement, la prévention et le diagnostic de la maladie d'Alzheimer. Cette capacité de liaison est apportée par la présence dans la formulation de lipides naturels particuliers identifiés par le demandeur. Ceux-ci comprennent une composante constante, constituée de cholestérol et de sphingomyéline, et un composant variable supplémentaire, constitué de lipides choisis.

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