A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 38/04 (2006.01) A61P 31/18 (2006.01)
Patent
CA 2317107
The incorporation of multiple branch peptide constructions having activity against HIV (such as those described in WO 95/07929 and WO 98/29443) into liposomes of sufficient size for white blood cell internalisation (e.g. greater than 150 nm and preferably approximately 250 to 400 nm) has been shown to increase the activity of those MBPCs manifold. The liposomes and pharmaceutical compositions containing them are claimed.
L'incorporation de constructions peptidiques à plusieurs ramifications, ayant une activité contre le VIH, (telles que celles décrites dans les demandes WO 95/07929 et WO 98/29443), dans des liposomes d'une taille suffisante pour l'internalisation des leucocytes (par ex. supérieure à 150 nm et de préférence comprise entre environ 250 et 400 nm) s'est avérée accroître à maintes reprises l'activité de ces constructions peptidiques à plusieurs ramifications. Les liposomes et les compositions pharmaceutiques les contenant sont également revendiqués.
Cellpep S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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