Liposomes containing phosphate glycerol groups for treating...

A - Human Necessities – 61 – K

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Details

A61K 31/662 (2006.01) A61K 9/127 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2533084

This invention provides a method for prophylaxis or treatment of an acute inflammatory disorder, comprising administering to a patient an effective amount of pharmaceutically acceptable bodies carrying an effective number of phosphate-containing groups presented or presentable on the surface of said bodies, the phosphate-containing groups comprising a plurality of phosphate- glycerol groups or groups convertible to such groups, to inhibit and/or reduce the progression of the acute inflammatory disorder, said bodies being of a size from about 20 nanometers (nm) to 500 micrometers (~m).

La présente invention a trait à un procédé pour la prévention ou le traitement d'un trouble inflammatoire aigu, comprenant l'administration à un patient d'une quantité efficace d'éléments pharmaceutiquement acceptables portant un nombre efficace de groupes contenant du phosphate présentés ou aptes à être présentés à la surface desdits éléments, les groupes contenant du phosphate comportant une pluralité de groupes glycérophosphate ou de groupes transformables en de tels groupes, pour l'inhibition et/ou la réduction de la progression d'un trouble inflammatoire aigu, lesdits éléments ayant une taille comprise entre environ 20 nanomètres (nm) à 500 micromètres (µm).

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