Liposomes for treatment of multiple myeloma

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/454 (2006.01) A61K 9/127 (2006.01) A61K 31/475 (2006.01) A61K 31/573 (2006.01) A61K 31/704 (2006.01)

Patent

CA 2622368

A method for treating multiple myeloma in newly diagnosed or previously treated patients is described. The method comprises administering a composition consisting of a combination of chemotherapeutic agents of an anthracycline antibiothic, preferably entrapped in a liposome, dexamethasone, and thalidomide, and, optionally, a reduced dose of vincristine.

L'invention concerne une méthode de traitement du myélome multiple chez des patients pour lesquels cette maladie a été récemment diagnostiquée, ou qui ont déjà été traités pour celle-ci. La méthode comporte l'administration d'une composition constituée d'une combinaison d'agents chimiothérapeutiques comprenant un antibiotique d'anthracycline, de préférence encapsulé dans un liposome, de la dexaméthasone et du thalidomide, et éventuellement une dose réduite de vincristine.

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