C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 317/22 (2006.01) A61K 31/192 (2006.01) A61K 31/216 (2006.01) A61K 31/357 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07C 59/66 (2006.01) C07C 69/708 (2006.01)
Patent
CA 2466418
This invention is directed to lipoxin A4 analogs of the following formulas (I) and (II), wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.
La présente invention concerne des analogues de lipoxine A¿4? de formules (I) et (II), dans lesquelles R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont tels que décrits dans l'invention. Ces analogues sont utilisés pour traiter des troubles inflammatoires et auto-immuns chez l'homme. Lesdits analogues sont également utilisés pour traiter une inflammation pulmonaire ou respiratoire chez l'homme.
Bauman John G.
Guilford William J.
Parkinson John F.
Skuballa Werner
Subramanyam Babu
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
Schering Aktiengesellschaft
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