Lipoxin compounds and their use

Details Lipoxin compounds and their use Lipoxin compounds and their use

C - Chemistry, Metallurgy

07

C

C07C 69/736 (2006.01) A61K 31/232 (2006.01) C07C 59/68 (2006.01)

Patent

CA 2365204

Aspirin* (ASA) triggers a switch in the biosynthesis of lipid mediators, inhibiting prostanoid production and initiating 15-epi-lipoxin generation, through the acetylation of cyclooxygenase II.

L'aspirine (acide acétylsalicylique) déclenche une commutation de la biosynthèse des médiateurs lipides. L'acétylation résultante de la cyclo-oxygénase II inhibe la production de prostanoïdes et amorce la génération de 15-épi-lipoxine.

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