Lipoxygenase enzyme inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 215/58 (2006.01) A61K 31/47 (2006.01) C07D 215/60 (2006.01) C07D 217/24 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1313376

4342 LIPOXYGENASE ENZYME INHIBITORS Abstract of the Disclosure The present invention is concerned with organic compounds which inhibit lipoxygenase enzymes. Hydroxy quinol-1-one and quinol-2-one based compounds found to be potent inhibitors of 5-. 12-, and 15- lipoxygenase enzymes. The present invention also relates to method of making such compounds, and to methods of inhibiting lipoxygenase enzymes inhuman and animal hosts in heed of such treatment.

534042

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