C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/226, 260/281
C07D 215/58 (2006.01) A61K 31/47 (2006.01) C07D 215/60 (2006.01) C07D 217/24 (2006.01) C07F 7/10 (2006.01)
Patent
CA 1313376
4342 LIPOXYGENASE ENZYME INHIBITORS Abstract of the Disclosure The present invention is concerned with organic compounds which inhibit lipoxygenase enzymes. Hydroxy quinol-1-one and quinol-2-one based compounds found to be potent inhibitors of 5-. 12-, and 15- lipoxygenase enzymes. The present invention also relates to method of making such compounds, and to methods of inhibiting lipoxygenase enzymes inhuman and animal hosts in heed of such treatment.
534042
Gunn Bruce Paul
Summers James B. Jr.
Abbott Laboratories
Goudreau Gage Dubuc
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