Lipoxygenase inhibiting compounds

C - Chemistry – Metallurgy – 07 – C

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260/452, 260/547

C07C 275/64 (2006.01)

Patent

CA 1304391

Case No. 4433 LIPOXYGENASE INHIBITING COMPOUNDS Abstract of the Disclosure Compounds of the formula: Image where R1 is amino or methyl; R2 is C1-C2 alkyl; R3 is one or more substituents selected from hydrogen, halogen or trihalomethyl; R4 is one or more substituents selected from hydrogen, halogen, trihalomethyl, C1 to C4 alkoxy or C1 to C4 alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C1 to C6 alkoyl are inhibitors of 5- and/or 12-lipoxygenase enzymes.

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