Lipoxygenase inhibiting compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/54 (2006.01) A61K 31/17 (2006.01) A61K 31/33 (2006.01) C07C 275/64 (2006.01) C07D 207/337 (2006.01) C07D 209/14 (2006.01) C07D 209/18 (2006.01) C07D 213/30 (2006.01) C07D 213/68 (2006.01) C07D 307/42 (2006.01) C07D 307/52 (2006.01) C07D 307/81 (2006.01) C07D 333/16 (2006.01) C07D 333/20 (2006.01) C07D 333/32 (2006.01) C07D 333/56 (2006.01) C07D 333/58 (2006.01) C07D 333/64 (2006.01) C07D 405/06 (2006.01) C07D 409/02 (2006.01) C07D 409/04 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2046872

2046872 9008545 PCTABS00001 Certain N-aryl-, N-heteroaryl-, N-arylalkyl-, N-heteroarylalkyl-, N-arylcyclopropyl- and N-heteroaryl-cyclopropyl-N'-hydroxyurea compounds are inhibitors of lipoxygenase enzyme activity and are thus useful agents in treating disease states such as asthma, arthritis, allergy, psoriasis, inflammatory bowel disease, gout, adult respiratory distress syndrome, endotoxin shock, and other inflammatory conditions in which the products of the arachidonic acid cascade are implicated.

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