Liquid aerosol formulations and aerosol generating devices...

B - Operations – Transporting – 01 – J

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B01J 2/04 (2006.01) A61K 9/72 (2006.01) A61K 31/137 (2006.01) A61K 31/58 (2006.01) A61K 47/10 (2006.01) A61M 11/00 (2006.01) A61M 15/00 (2006.01) B05B 7/16 (2006.01)

Patent

CA 2497845

Liquid aerosol formulations for generating aerosols include at least one high volatility carrier and a second component. In some embodiments, the liquid aerosol formulation is propellant free. An aerosol generating device generates an aerosol by passing liquid aerosol formulation through a flow passage heated to convert the liquid into a vapor, which is mixed with air to form an aerosol. In some embodiments, particles of the aerosol consist essentially of the second component. The aerosol generator can be incorporated in a hand held inhaler. The aerosol can be delivered to a targeted portion of the lung using the inhaler.

L'invention concerne des formulations liquides d'aérosol permettant de générer des aérosols comprenant au moins un support à forte volatilité et un second composant. Dans certains modes de réalisation, la formulation liquide d'aérosol est exempte de propergol. Un générateur d'aérosol génère un aérosol en faisant passer une formulation liquide d'aérosol à travers un passage d'écoulement chauffé de manière à transformer le liquide en vapeur, mélangée à de l'air afin de former un aérosol. Dans certains modes de réalisation, des particules de l'aérosol sont essentiellement constituées du second composant. Le générateur d'aérosol peut être incorporé dans un inhalateur à main. L'aérosol peut être administré dans une position ciblée du poumon à l'aide de l'inhalateur.

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