G - Physics – 01 – N
Patent
G - Physics
01
N
73/93
G01N 30/96 (2006.01) G01N 30/46 (2006.01) G01N 30/60 (2006.01)
Patent
CA 1166470
LIQUID CHROMATOGRAPHY APPARATUS AND METHOD EMPLOYING ION CONCENTRATION Abstract of the Disclosure Apparatus and method for chromatographic separation and quantitation of different ions of like charges in a sample, e.g., cations or anions. Referring to anion separation, a sample including at least one highly ionized (strong ) weak anion and at least two poorly ionized (weak) cations (or vice versa) is directed with a developing reagent through an ion exchange separation column in which the weak anions, separated as a group from the strong ones, are directed to a suppressor ion exchange bed in which the developing reagent is converted to a weakly ionized form. The strong acids are directed to an anion concentrator column which retains the anions but passes the remainder of the solution. Thereafter, the weak anions are dissolved in a developing reagent and separated on a chromatographic separation column. The resolved anions are then directed to a detector. If the detector is of the type employing a conductivity cell, the solution is passed through a second suppressor column prior to the detector.
375827
Johnson Edward L.
Rich William E. Jr.
Dionex Corporation
Smart & Biggar
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