Liquid chromatography with tandem mass spectrometry of...

Details Liquid chromatography with tandem mass spectrometry of... Liquid chromatography with tandem mass spectrometry of...

G - Physics

01

N

G01N 33/74 (2006.01) G01N 30/72 (2006.01) G01N 33/78 (2006.01)

Patent

CA 2654319

Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the analysis of endogenous biomarkers, including steroid hormones, such as estrone and estradiol, thyroid hormones, such as free thyroxine, and metabolites, such as 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3, in biological samples.

Procédés et systèmes reposant sur l'emploi d'une chromatographie liquide/spectrométrie de masse en tandem (LC-MS/MS et 2D-LC-MS/MS) pour l'analyse de marqueurs biologiques dans des échantillons biologiques, notamment des stéroïdes hormonaux telles qu'estrone et estradiol, des hormones thyroïdienne telles que la thyroxine libre, et des métabollites tels que la 25-hydroxyvitamine D2 et la 25-hydroxyvitamine D3.

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