Liquid composition of cisplatin coordination compound

A - Human Necessities – 61 – K

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A61K 33/24 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C08G 69/40 (2006.01) C08G 81/00 (2006.01)

Patent

CA 2728502

A liquid composition containing a polymer micelle and having a pH values of 3.0 to 7.0 is provided. The micelle is constituted of a coordination compound having a block copolymer of polyethylene glycol and polyglutamic acid and cisplatin that is coordinate-bonded to the block copolymer.

L'invention porte sur une composition liquide. La composition liquide comprend une micelle polymère renfermant un composé coordonné composé dun copolymère à blocs de polyéthylène glycol et d'acide polyglutamique; et de la cisplatine fixée au copolymère à blocs par une liaison de coordination. La composition liquide est également caractérisée en ce que son pH est compris entre 3,0 et 7,0.

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