Liquid composition of factor vii polypeptides

Details Liquid composition of factor vii polypeptides Liquid composition of factor vii polypeptides

A - Human Necessities

61

K

A61K 38/36 (2006.01) A61K 38/48 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) C07K 14/745 (2006.01)

Patent

CA 2470511

A liquid aqueous composition comprising (i) a factor VII polypeptide, (ii) an agent suitable for keeping pH in the range of from about 4.0 to about 8.0; (iii) an agent selected from the list of: a calcium salt, a magnesium salt, or a mixture thereof; wherein the concentration of (iii) is at least 15 mM.

L'invention concerne une composition aqueuse liquide renfermant (i) un polypeptide de facteur VII, (ii) un agent approprié pour maintenir le pH dans une fourchette comprise entre environ 4,0 et 8,0, (iii) un agent sélectionné parmi la liste comprenant un sel de calcium, un sel de magnésium ou un mélange correspondant, la concentration de (iii) étant d'au moins 15 mM.

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