Liquid composition of modified factor vii polypeptides

Details Liquid composition of modified factor vii polypeptides Liquid composition of modified factor vii polypeptides

A - Human Necessities

61

K

A61K 38/36 (2006.01) A61K 38/48 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) C07K 14/745 (2006.01)

Patent

CA 2470313

The invention provides a liquid, aqueous composition, comprising (i) a modified factor VII poly-peptide; (ii) an agent suitable for keeping pH in the range of from about 4.0 to about 8.0; (iii) an antioxidant; and (iv) an agent selected from the list of: a calcium salt, a magnesium salt, or a mixture thereof.

L'invention concerne une composition liquide, aqueuse comprenant (i) un polypeptide VII à facteur modifié; (ii) un agent permettant de conserver le pH entre environ 4 et 8; (iii) un antioxydant; (iv) un agent choisi dans la liste constituée d'un sel de calcium, d'un sel de magnésium, ou d'un mélange de ceux-ci.

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