Liquid dosage forms of proton pump inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4439 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2490145

Liquid formulations of acid-labile drugs are provided. The formulations generally comprise micro-granules comprising an acid-labile drug coated with an enteric coating and a liquid vehicle having a pH less than 6Ø The components of the formulation can separately provided in the form of kits. The formulations and kits may be used to treat patients suffering from disorders for which the acid labile drugs are indicated.

L'invention concerne des formulations liquides de médicaments labiles acides. Ces formulations comprennent généralement des microgranules qui contiennent un médicament labile acide recouvert d'un revêtement gastro-résistant et un véhicule liquide ayant un pH inférieur à 6,0. Les composants de la formulation peuvent se présenter séparément sous la forme de trousses. Les formulations et les trousses selon l'invention peuvent servir à traiter des patients qui souffrent de troubles pour lesquels ces médicaments labiles acides sont indiqués.

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