Liquid formulation based on a guanidinoacetic acid component

A - Human Necessities – 23 – L

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Details

A23L 1/305 (2006.01) A23L 1/302 (2006.01) A23L 2/52 (2006.01) A61K 31/155 (2006.01) A61K 31/198 (2006.01) A61K 31/205 (2006.01)

Patent

CA 2614711

The present invention relates to a liquid formulation for human and animal nutrition, consisting of an aqueous solution, a guanidinoacetic acid component and at least one methyl group donor from the group of choline, methionine and betaine. In addition to the free guanidinoacetic acid, it is also possible to use salts, adducts and/or complexes as the guanidinoacetic acid component, which can additionally be combined with further physiologically active compounds. Since the guanidinoacetic acid component is present in dissolved form, formulations including those in the form of mineral water, lemonade, alcoholic drinks and drinking water formulations are envisaged. It has been found that, surprisingly, the guanidinoacetic acid component present in this liquid formulation has very good stability and is converted very rapidly to creatine in the body.

La présente invention concerne une formulation liquide pour la nutrition humaine et animale, laquelle formulation est constituée d'une solution aqueuse, d'un constituant acide guanidinoacétique et d'au moins un donneur de groupe méthyle de la série choline, méthionine et betaïne. Outre l'acide guanidinoacétique libre, il est possible d'utiliser également, comme constituant acide guanidinoacétique, des sels, des composés d'addition et/ou des composés complexes pouvant être également combinés à d'autres composés physiologiquement actifs. Etant donné que le constituant acide guanidinoacétique est présent sous forme dissoute, des préparations sous forme d'eau minérale, de limonade, de boissons alcoolisées et de préparations à base d'eau de consommation sont prévues. Il est apparu, de manière surprenante, que le constituant acide guanidinoacétique, contenu dans cette formulation liquide, possède une très bonne stabilité et se transforme très rapidement en créatine dans le corps.

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