A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7068 (2006.01) A61K 9/14 (2006.01) A61K 31/7072 (2006.01) A61K 47/10 (2006.01)
Patent
CA 2488108
Pharmaceutical formulations, kits and vessels are provided for delivering decitabine to a patient suffering from a disease in need of treatment with decitabine. The pharmaceutical formulation comprises decitabine solvated in a non-aqueous solvent that comprises glycerin, propylene glycol, polyethylene glycol, or combinations. Such formulations are more chemically stable than conventional liquid formulations of decitabine containing more than 40% water in volume. The pharmaceutical formulations can be used for any disease that is sensitive to the treatment with decitabine, such as hematological disorders and cancer.
L'invention porte sur une préparation pharmaceutique et des trousses et des récipients associés servant à administrer de la décitabine à un patient le nécessitant. Ladite préparation comprend de la décibatine dissoute dans un solvant non aqueux comprenant de la glycérine, du propylène glycol, du polyéthylène glycol, ou leur combinaison combinaisons. Une telle préparation est plus stable chimiquement que les préparations liquides usuelles de décitabine contenant plus de 40 % d'eau en volume. Une telle préparation peut traiter toute maladie sensible à un traitement par la décitabine, dont les troubles hématologiques et le cancer.
Gong Stephanie
Gore Ashok Y.
Joshi-Hangal Rajashree
Redkar Sanjeev
Zhang Xichen
Borden Ladner Gervais Llp
Supergen Inc.
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