Liquid interferon-.beta. formulations

Details Liquid interferon-.beta. formulations Liquid interferon-.beta. formulations

A - Human Necessities

61

K

A61K 38/21 (2006.01) A61K 9/08 (2006.01)

Patent

CA 2304808

The invention relates to liquid formulations of human interferon-.beta.. The inventive formulations are characterised in that they have a buffer with a pH value in the slightly acidic to neutral range between 5 and 8, preferably between 5.5 and 8, and in that the interferon-.beta. is highly stable in solution, the molecular integrity being preserved.

L'invention concerne des formulations liquides d'interféron .beta. humain. Les formulations se caractérisent en ce qu'elles présentent un tampon ayant un pH compris entre une plage faiblement acide à neutre de l'ordre de 5 à 8, de préférence supérieure à 5,5 et 8 et que l'interféron .beta. est très stable en solution, l'intégrité moléculaire étant maintenue.

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