Liquid pharmaceutical formulation containing zotepine

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/38 (2006.01) A61K 9/00 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2320475

A liquid pharmaceutical formulation comprising a) 2 to 7% w/v of Zotepine; b) 0.5 to 35% w/v of an organic acid selected from the group consisting of ascorbic acid, citric acid, fumaric acid, glutaric acid, lactic acid, malic acid, sorbic acid and tartaric acid; c) 15 to 60% v/v of ethanol and d) a liquid diluent to 100%; which may be used as drops or in a drink.

L'invention concerne une formulation pharmaceutique liquide comprenant: a) de 2 à 7 % m/v de Zotépine; b) de 0,5 à 35 % m/v d'un acide organique sélectionné dans le groupe constitué de l'acide scorbique, de l'acide citrique, de l'acide fumarique, de l'acide glutarique, de l'acide lactique, de l'acide malique, de l'acide sorbique et de l'acide tartrique; c) de 15 à 60 % v/v d'éthanol et d) ladite formulation est complétée à 100 % par un diluant liquide. La formulation peut être utilisée sous forme de gouttes ou dans une boisson.

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