Liquid phase oxidation of esters to form carboxylic acids...

C - Chemistry – Metallurgy – 07 – C

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260/518, 260/528

C07C 51/09 (2006.01) B01J 31/04 (2006.01) C07C 51/23 (2006.01)

Patent

CA 1038403

ABSTRACT OF THE DISCLOSURE An improved liquid phase oxidation process wherein greater amounts of esters such as ethyl acetate are converted to carboxylic acids such as acetic acid by forming a liquid reation mixture comprising the ester and sufficient water to allow hydrolysis of the ester during the oxidation re- action. Addition of at least one ketone such as methyl ethyl ketone and optionally at least one aldehyde such as acetaldehyde to the reation mix- ture improves conversion rates. In a particularly advantageous embodiment, a liquid reaction feed mixture comprising from about 30 to 40% ethyl acetate, about 45 to 50% methyl ethyl ketone, and about 5 to 10% acetaldehyde is ox- idized in the presence of about 5 to 10% water to acetic acid using air, cobalt acetate catalyst, and acetic acid reaction medium.

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