A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/34 (2006.01) A61K 9/08 (2006.01) A61K 45/08 (2006.01)
Patent
CA 2324265
Controlled release of hydrophobic bioactive substances in vivo over an extended time period and without "bursts" of drug release is achieved using a liquid polymeric composition including a polymer such as poly(lactide-co-glycolide) copolymer in a mixture of hydrophilic and lipophilic solvents.
Selon cette invention, on réalise la libération contrôlée de substances bioactives hydrophobes in vivo sur une durée prolongée et sans libération du médicament "en rafales" à l'aide d'une composition polymère liquide comprenant un polymère tel qu'un copolymère poly(lactide-co-glycolide) dans un mélange de solvants hydrophiles et lipophiles.
Chern Rey T.
Zingerman Joel R.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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