A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/57 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2137258
ABSTRACT OF THE DISCLOSURE A liquid preparation of antithrombin-III (AT-III), comprising an AT-III and an organic acid, a salt thereof, a sugar sulfate or a surfactant as a stabilizer, and a liquid preparation of AT-III, having a pH of 9-10. The preparation of the present invention is stable after long-term preservation and poses no clinical problems in terms of pharmacological effects and safety. The preparation is more advantageous than lyophilized preparations in that it does not require dissolution in injectable distilled water and can be used easily. Accordingly, the preparation is clinically very useful. 3 5
Fukuyama Hajime
Ohmizu Akimasa
Takechi Kazuo
Uriyu Katsuhiro
Yokoyama Kazumasa
Fetherstonhaugh & Co.
Welfide Corporation
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