A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 9/19 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2692231
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
L'invention porte sur des formulations liquides de protéines morphogénétiques d'os pour une utilisation prolongée à des températures élevées. De façon plus précise, l'invention porte sur des formulations liquides comprenant rhGDF-5, du tréhalose et un ou plusieurs excipients biocompatibles qui présentent une stabilité à la protéine pendant au moins 30 jours à des températures allant jusqu'à la température corporelle.
Garigapati Venkat
Lopez Julius
Su Dongling
Advanced Technologies And Regenerative Medicine Llc
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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