Liquid stable thiol activator

Details Liquid stable thiol activator Liquid stable thiol activator

C - Chemistry, Metallurgy

12

Q

C12Q 1/50 (2006.01)

Patent

CA 2165808

An aqueous, liquid-stable thiol activator solution is disclosed. The solution can include a thiol activator, such as N-acetyl-L-cysteine and a stabilizing agent, such as mannitol. The thiol is stabilized in the aqueous solution for at least about one year under storage conditions and for at least about 28 days under open-bottle conditions. The solution can be used as a reactivator of creatine kinase catalytic activity.

Cette invention se rapporte à une solution d'activateur au thiol aqueuse et stable en phase liquide, qui peut contenir un activateur au thiol, tel que N-acétyl-L-cystéine, ainsi qu'un agent de stabilisation, tel que du mannitol. Le thiol est stabilisé dans la solution acqueuse pour au moins une année environ dans des conditions de stockage en récipient fermé et pour au moins vingt huit jours environ dans des conditions de stockage en récipient ouvert. Une telle solution peut être utilisée comme réactivateur de l'activité catalytique de la créatine-kinase.

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