Liquid suspensions of nitrofurantoin

Details Liquid suspensions of nitrofurantoin Liquid suspensions of nitrofurantoin

A - Human Necessities

61

K

167/239

A61K 31/415 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2020812

Compositions, for the administration of nitrofurantoin to a human or other animal subject, comprising: (a) a safe and effective amount of nitrofurantoin particulates having a surface consisting of nitrofurantoin monohydrate, wherein said particulates have a mean particle size greater than about 200 mesh size; (b) nitrofurantoin monohydrate; (c) an effective amount of a suspending agent; and (d) water; wherein the pH of said composition is from about 1 to about 6; and said nitrofurantoin monohydrate is dissolved in said water at saturation level. The nitrofurantoin of this invention are highly efficacious for the oral delivery of nitrofurantoin.

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