C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2395832
The present invention concerns compositions and methods for the treatment of disorders characterized by the overexpression of an LIV-1. More specifically, the compositions include DNA and amino acid sequences of an LIV-1, antibodies to an LIV-1, and methods for the treatment of a mammal susceptible to or diagnosed with cancer wherein an LIV-1 is overexpressed.
La présente invention concerne des compositions et des méthodes de traitement de troubles caractérisés par la surexpression d'un gène LIV-1, plus particulièrement, les compositions renfermant des séquences d'acides aminés et d'ADN d'un gène LIV-1, des anticorps d'un gène LIV-1, ainsi que des méthodes destinées au traitement d'un mammifère susceptible d'avoir un cancer, où un gène LIV-1 est surexprimé, ou d'un mammifère chez qui on a diagnostiqué ce type de cancer.
de Sauvage Frederic
Goddard Audrey
Gurney Austin L.
Hongo Jo-Anne S.
Smith Victoria
Genentech Inc.
Smart & Biggar
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