Live attenuated venezuelan equine encephalitis vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/04 (2006.01) A61K 39/193 (2006.01) A61P 31/12 (2006.01) C07K 14/18 (2006.01)

Patent

CA 2354374

A live attenuated Venezuelan equine encephalitis virus (VEE) is described which comprises a viral gene rearrangement. This rearranged attenuated virus is useful as vaccine for protection against infection with VEE. Methods of preparing the virus and methods of using the virus are described.

L'invention concerne le virus de l'encéphalomyélite équine du Venezuela (EEV), qui comprend un réarrangement génétique viral. Le virus atténué réarrangé est utilisé comme vaccin de protection contre une infection par l'EEV. L'invention concerne également des procédés de préparation et d'utilisation du virus.

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