Live genetically attenuated malaria vaccine

Details Live genetically attenuated malaria vaccine Live genetically attenuated malaria vaccine

C - Chemistry, Metallurgy

07

K

C07K 14/445 (2006.01) A61K 39/015 (2006.01) C12N 15/30 (2006.01)

Patent

CA 2551193

Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.

L'invention concerne un procédé pour immuniser un hôte vertébré contre la malaria, comprenant l'administration à l'hôte d'un organisme vivant, un Plasmodium, génétiquement modifié, de manière à interrompre une fonction du gène spécifique du foie.

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