Live influenza virus vaccines and preparation thereof

Details Live influenza virus vaccines and preparation thereof Live influenza virus vaccines and preparation thereof

A - Human Necessities

61

K

167/132

A61K 39/145 (2006.01)

Patent

CA 1047922

ABSTRACT OF THE DISCLOSURE Attenuated stable influenza type B virus strains are obtained by recombining a vaccinal and previously attenuated influenza type B virus strain with an influenza type B virus isolate having the desired serotype and iso- lating a recombinant having at least one marker property of the attenuated parent strain which is not shared by the other parent strain and the antigenic composition of the other parent strain. The obtained strains are useful for the production of nasal influenza vaccines.

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