C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/867 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07K 14/16 (2006.01) C12N 15/12 (2006.01) C12N 15/30 (2006.01) C12N 15/31 (2006.01) C12N 15/33 (2006.01) C12N 15/86 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2492131
The present invention provides a vector or vector containing composition comprising a spumavirus backbone and a antigen-encoding nucleic acid. The present invention also provides methods of treating or preventing a condition resulting from a viral, bacterial, or parasitic infection in a subject comprising administering to the subject an effective amount of the vector or vector containing composition comprising a spumavirus backbone and an antigen- encoding nucleic acid. Also provided in the present invention are methods of treating a condition resulting from a cancer in a subject comprising administering to the subject an effective amount of the vector or vector containing composition comprising a spumavirus backbone and an antigen- encoding nucleic acid.
La présente invention concerne un vecteur ou une composition contenant un vecteur qui comprend un squelette de spumavirus et un acide nucléique codant l'antigène. Cette invention se rapporte également à des méthodes de traitement ou de prévention d'un état résultant d'une infection virale, bactérienne ou parasitaire chez un sujet, qui consistent à administrer au sujet, une quantité efficace du vecteur de la composition contenant le vecteur comprenant un squelette de spumavirus et un acide nucléique codant l'antigène. Cette invention concerne également des méthodes de traitement d'un état résultant d'un cancer chez un sujet, lesdites méthodes consistant à administrer au sujet une quantité efficace du vecteur ou d'une composition contenant le vecteur comprenant un squelette de spumavirus et un acide nucléique codant l'antigène.
Chen Irvin S. Y.
Folks Thomas M.
Gowling Lafleur Henderson Llp
The Government Of The United States Of America As Represented By The Se Cretary Department Of Health And Human
The Regents Of The University Of California
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