C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) A61K 39/02 (2006.01) A61K 39/112 (2006.01) C12N 1/21 (2006.01) C12N 9/52 (2006.01) C12N 15/00 (2006.01)
Patent
CA 2079463
Attenuated microorganism for use in immunoprophylaxis in which the attenuation is brought about by the presence of a mutation in the DNA sequence of the microorganism which encodes, or which regulates the expression of DNA encoding a pro- tein that is produced in response to environmental stress, the microorganism optionally being capable of expressing DNA encod- ing a heterologous antigen.
Charles Ian G.
Chatfield Steven N.
Dougan Gordan
Hormaeche Carlos E.
Johnson Kevin S.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Wellcome Foundation Limited
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