Liver disease-related methods and systems

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2566914

The invention provides diagnostic methods, kits, and systems, and related computer-readable media, which use multiple blood marker values, including serum and plasma marker values, to aid in the diagnosis of the status or progress of a liver disease in a patient. The invention also provides methods and systems, and related computer-readable media, that use blood marker values, including serum and plasma marker values: (1) to screen for active ingredients useful in the treatment of a liver disease; (2) to aid in the selection of treatment regimens for patients that are predisposed to, or suffer from, liver disease; and (3) to aid in the design of clinical programs useful in monitoring the status or progress of liver disease in one or more patients.

L'invention concerne des méthodes de diagnostic, des trousses et des systèmes, ainsi que des supports associés lisibles par ordinateur, lesquels font appel à des valeurs de marqueurs sanguins, notamment des valeurs de marqueurs sériques et plasmatiques, pour aider à diagnostiquer l'état ou la progression d'une maladie hépatique chez un patient. L'invention concerne également des méthodes des systèmes, et des supports associés lisibles par ordinateur, dans lesquels les valeurs de marqueurs sanguins, notamment les valeurs de marqueurs sériques et plasmatiques sont utilisés pour: (1) identifier par criblage des ingrédients actifs pouvant servir au traitement d'une maladie hépatique; (2) aider à choisir les schémas de traitement des patients prédisposés à une maladie hépatique ou souffrant d'une telle maladie; et (3) aider à mettre au point des programmes cliniques permettant de surveiller le stade ou l'évolution d'une maladie hépatiques chez un ou plusieurs patients.

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