C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) C12N 5/071 (2010.01) A61K 35/407 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2451637
A substantially enriched mammalian hepatic liver engrafting cell population is provided. Methods are provided for the isolation and culture of this liver engrafting cell. The progenitor cells are obtained from a variety of sources, including fetal and adult tissues. The cells are useful in transplantation, for experimental evaluation, and as a source of lineage and cell specific products, including mRNA species useful in identifying genes specifically expressed in these cells, and as targets for the discovery of factors or molecules that can affect them.
L'invention concerne une population de cellules de greffe hépatique de mammifères sensiblement enrichies. L'invention concerne également des procédés d'isolement et de culture de cette cellule de greffe hépatique. Les cellules souche sont obtenues à partir d'une variété de sources, notamment des tissus de foetus ou d'adulte. Les cellules sont utiles en transplantation pour l'évaluation expérimentale. Ces cellules sont également utiles en tant que source de lignage et de produits spécifiques de cellules, notamment d'espèces d'ARN messager permettant l'identification de gènes exprimés spécifiquement dans ces cellules, ainsi qu'en tant que cibles permettant la découverte de facteurs ou de molécules qui peuvent les affecter.
Austin Timothy
Lagasse Eric
Fetherstonhaugh & Co.
Stemcells Inc.
LandOfFree
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