Liver fat accumulation inhibitory composition, food additive...

Details Liver fat accumulation inhibitory composition, food additive... Liver fat accumulation inhibitory composition, food additive...

A - Human Necessities

61

K

A61K 31/201 (2006.01) A23L 1/30 (2006.01) A61K 31/20 (2006.01) A61K 31/23 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2302641

A method of inhibiting liver fat accumulation which comprises administering a conjugated linoleic acid homolog to a mammal or making the mammal ingest it; and liver fat accumulation inhibitory composition characterized by containing an effective amount of a conjugated linoleic acid homolog together with a support for medicinal preparations or foods. The administration or ingestion of CLA inhibits the total lipid content and the triglyceride content in the liver from increasing, and hence can effectively prevent diseases attributable to fatty liver, such as chronic hepatitis and hepatic cirrhosis.

Cette invention concerne un procédé qui permet de bloquer l'accumulation des graisses par le foie, et qui consiste à administrer au mammifère, ou à lui faire ingérer, un homologue de l'acide linoléique à conjugaison diène. L'invention concerne également une composition bloquant l'accumulation des graisses par le foie, laquelle composition contient spécifiquement une quantité suffisante d'un homologue de l'acide linoléique à conjugaison diène en association avec un support pour préparations médicinales ou des aliments. En bloquant la progression des niveaux de triglycérides et de lipides totaux du foie, l'administration ou l'ingestion d'acide linoléique à conjugaison diène (CLA) permet de prévenir de façon satisfaisante la survenue de pathologies imputables à la stéatose hépatique telles que l'hépatite chronique et la cirrhose hépatique.

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