A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/665 (2006.01)
Patent
CA 2135088
A liver protectant comprising a phosphoric diester compound of the following formula (wherein R1 and R2 are the same or different and each represents hydrogen or methyl) or a pharmacologically acceptable salt thereof. Image The liver protectant composition of this invention effectively inhibits the elevation of GOT and GPT, among other parameters, so that it is useful for the prevention and therapy of acute liver disorder, chronic liver disorder and fulminant liver disorder. It can also be used in cirrhosis of the liver with success. The liver protectant composition of this invention can be used with advantage in liver damage associated with alcohol intake and hepatic impairment due to acetaminophen and other drugs. Furthermore, the liver protectant composition of this invention is of value in acute intrahepatic cholestasis.
Matsuura Sachiko
Nagao Rie
Ogata Kazumi
Ogino Shinya
Sakaue Takahiro
Kirby Eades Gale Baker
Senju Pharmaceutical Co. Ltd.
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