Liver stem cell

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) C12N 5/0735 (2010.01) C12N 5/074 (2010.01) A61K 35/407 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2336958

The invention provides a primary liver stem cell and a cell doublet consisting of a hepatocyte and the stem cell, both of which are derived from normal liver tissue. Methods of isolating the cells, genetically altering the cells, and using the cells for transplantation are also within the invention.

L'invention concerne une cellule embryonnaire hépatique primaire et un doublet cellulaire constitué d'un hépatocyte et de la cellule embryonnaire, émanant l'un et l'autre de tissu hépatique normal. L'invention concerne en outre des procédés relatifs à l'isolation des cellules, à la modification génétique des cellules, et à l'utilisation des cellules aux fins de transplantation.

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