Loc169505 as modifier of the apc and axin pathways and...

Details Loc169505 as modifier of the apc and axin pathways and... Loc169505 as modifier of the apc and axin pathways and...

G - Physics

01

N

G01N 33/53 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2506959

Human LOC169505 genes are identified as modulators of the APC and axin pathways, and thus are therapeutic targets for disorders associated with defective APC and axin function. Methods for identifying modulators of APC and axin, comprising screening for agents that modulate the activity of LOC169505 are provided.

La présente invention concerne des gènes LOC169505 humains, identifiés en tant que modulateurs des voies APC et axine. De ce fait, ces gènes représentent des cibles thérapeutiques pour des troubles associés à la fonction défectueuse de APC et axine. L'invention concerne des méthodes permettant d'identifier les modulateurs de APC et d'axine, lesquelles méthodes consistent à cribler des agents qui modulent l'activité du gène LOC169505.

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